VIA demonstrated a new size of EPIA motherboard at CES this year measuring just 100 x 72mm - the Pico-ITX. The prototype EPIA PX was powered by a 1GHz C7 CPU and an unnamed chipset with Unichrome Pro II functionality, making it both smaller and potentially slightly faster than current 120 x 120mm Nano-ITX boards.
It's unclear when the Pico-ITX will make an appearance but when it does VIA hopes it will be incorporated inside places such as vehicles, wireless or even skype devices.
Due to the small size most I/O will require cables attached to pin headers. Provisional specifications are: 1x DDR2 SODIMM socket; IDE; SATA; VT6106S 10x100 LAN with RJ45 socket; VGA socket; VT1708A Audio; 4x USB 2.0; COM; PS2; LVDS/DVI; TV output headers.